Fig. 1From: The plasmid-mediated evolution of the mycobacterial ESX (Type VII) secretion systemsThe phylogeny of the ESX gene cluster. Maximum likelihood phylogeny of representative ESX gene clusters describing the evolution of the ESX gene cluster from its WXG-FtsK cluster progenitor. The ESX gene clusters form five groups, ESX-4, ESX-3, ESX-1, ESX-2 and ESX-5. The plasmid located and ancestral ESX gene clusters form subgroups of each genomic ESX gene cluster. The ESX gene clusters have evolved divergently from a single duplication of ESX-4 to ESX-1 and ESX-3 and then ESX-2 and ESX-5. One hundred subsets were generated for bootstrapping resampling of the dataBack to article page