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Fig. 3 | BMC Evolutionary Biology

Fig. 3

From: Rab32 and Rab38 genes in chordate pigmentation: an evolutionary perspective

Fig. 3

Rab32 and Rab38 synteny conservation in gnathostomes. The Rab32 (a) and Rab38 (b) loci harbour several genes (grey boxes) conserved across evolution; in blue boxes Rab genes we studied, in red boxes Rab38 genes that are physically linked to tyrosinase (green). During the gnathostome evolution, the Rab32 is always linked to Grm1, while Rab38 is linked to Grm5. The scheme 3b shows the functional relationship between Rab38 and Tyr during mammalian melanosome biogenesis (adapted from [55]). The position of the genes above or below the chromosome (horizontal line) indicates their transcriptional orientation on positive or negative strand, respectively

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