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Table 2 Parameter estimates for the evolutionary analysis of the schizothoracine EPO

From: Analysis of the erythropoietin of a Tibetan Plateau schizothoracine fish (Gymnocypris dobula) reveals enhanced cytoprotection function in hypoxic environments

Models Estimate of parameters Positively selected sites P value
Branch model
free-ratio (see Fig. 3 for ω values for each node) −2272.00 None  
Branch-site models (LRT for branch-site: 0.20)
 Model Null p0 = 0.19, p1 = 0.08 (p2 + p3 = 0.73), ω0 = 0.14, ω1 = 1.00, ω3 = 1.00 −2267.82 None  
 Model A p0 = 0.48, p1 = 0.21(p2 + p3 = 0.31), ω0 = 0.14, ω1 = 1.00, ω3 = 2.45 −2267.72 117 L (p = 0.727), 131H (p = 0.621) 0.6547
    133 T (p = 0.719), 138S (p = 0.797) (df = 1)
    153 L (p = 0.571)  
  1. The branch-site model in codeml program divides all the sites into four classes, class 0, 1, 2, and 3. Class 0 is for the sites under purifying selection. Class 1 is for the sites under neutral selection. Class 2 and 3 are for the sites that have positive selection in foreground branches. In this table, p 0 and ω0 stand for the percentage and averaged omega value of class 0 sites in the alignment. P 1 and ω1 stand for the percentage and averaged omega value of class 1 sites. P 2 + p 3 and ω2 + ω3 are for the percentage and averaged omega value of the sites in class 2 and 3