Fig. 2
From: Dynamics of bacterial insertion sequences: can transposition bursts help the elements persist?
Two simulation runs showing changes in IS copy number and cell fitness under transposition burst with evolving regulation. Transposition burst occurs at 5000th generation, and is gradually down-regulated over time thereafter. ISs may persist (left) or go extinct (right) at the end of 30,000. Top panels: mean IS copy per genome in the population is drawn in black with its 5 % and 95 % quantiles coloured in grey. Bottom panels: mean fitness of the population increases over time (black) with its 5 % and 95 % quantiles coloured in grey. The population is initialised with α ISs in β cells according to Sawyer et al. [62]. Other parameter values are as given in Table 1