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Table 4 Kruskal-Wallis test for equality of frequency of the slow acetylation phenotype across geographical regions, linguistic families, subsistence modes, and climatic zones

From: Variation in NAT2 acetylation phenotypes is associated with differences in food-producing subsistence modes and ecoregions in Africa

Dataset1 Categories grouping2 Number of populations Number of groups Kruskal-Wallis H statistic P-value3
AFR Geo4 37 3 2.38 0.3039
  Lang 38 4 7.13 0.0680
  Subsist 38 4 15.62 0.0014 (0.0056)
  Clim 38 2 13.17 0.0003 (0.0012)
FP5 Geo4 28 3 2.52 0.2843
  Lang 29 3 3.61 0.1649
  Subsist 29 3 8.25 0.0161 (0.0644)
  Clim 29 2 7.74 0.0054 (0.0216)
FPLS Geo 13 3 0.33 0.8480
  Lang5 12 2 1.15 0.2827
  Subsist 13 2 5.90 0.0152 (0.0608)
  Clim 13 2 6.43 0.0112 (0.0448)
  1. 1 As described in Methods, the three population data subsets are AFR: 38 samples, excluding the 1KG Americans of African ancestry (ASW, see Table 1); FP: 29 samples of African food-producing populations; FPLS: 13 samples of African food-producing populations with sample size ≥ 20 individuals. Thus, the ASW sample was not considered in any of the Kruskal-Wallis tests
  2. 2 Categories as in Table 1 : classification according to geographical region (Geo), subsistence mode (Subsist), linguistic affiliation (Lang), and ecoregion (Clim), namely climatic zone and biome, which defines the fourth categorization criterion that considers whether populations live within the dry savanna biome or outside of it
  3. 3 Significant P-values (i.e., <5 %) are shown in bold, and adjusted P-values after Bonferroni correction for multiple testing (here, four tests) are provided in brackets
  4. 4 Only three geographical regions are considered here (Western, Central and Eastern, Table 1) because the fourth region (Northern) is represented by one population sample only (EGY)
  5. 5 Only two linguistic families are considered here (Niger-Congo and Nilo-Saharan, Table 1) because the third family (Afro-Asiatic) is represented by one population sample only (SOM)