Fig. 9
From: Ancestral role of Pax2/5/8 in molluscan brain and multimodal sensory system development
Expression of Ino-Pax2/5/8 during early prehatching development of the cephalopod Idiosepius notoides. Dorsal (d)–ventral (v), anterior (ant)-posterior (p), and left (l)-right (r) axes indicate the orientation. a Ino-Pax2/5/8 is expressed in the mantle (m), the funnel (fn), and all five arm pairs (here only expression in arm pairs 4–5 visible) of stage 19 individuals. Note the faint Ino-Pax2/5/8 expression in the gills (arrowheads). b Same specimen as shown in (a) with Ino-Pax2/5/8 expression in the 2-5th arm pair (2–5). c Lateral view of same specimen as shown in (a) and (b) exhibiting expression of Ino-Pax2/5/8 in all five arm pairs (1–5). d Stage 21 individuals show Ino-Pax2/5/8 expression in the mantle, the fifth arm pair (5), and the funnel. Note the faint Ino-Pax2/5/8 expression in the gills (arrowheads). e Ino-Pax2/5/8 expression in portions of the optic ganglia (arrowheads) close to the eyes (ey) in the same specimen as shown in (d) f Same specimen as shown in (d-e) with Ino-Pax2/5/8 expression in the cerebral ganglia (cg). g Lateral view of the same specimen as shown in (d-f) Inset shows detail of Ino-Pax2/5/8 expression in the arms (arrowheads). Abbreviations: y, yolk sac. Scale bars: (a-g) 150 μm