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Table 3 Direction of selection (DoS) statistic for 20 genes involved in three different categories of RNAi knockdown phenotype

From: The effects of natural selection across molecular pathways in Drosophila melanogaster

Gene

Phenotype categoriesa

D N

D S

P N

P S

DoS

u-shaped

CR-IM-SR

9

25

5

34

0.137

kayak

SR-IM-IS

5

11

5

26

0.151

α COP

SR-IM-IS

2

16

5

67

0.042

E(Pc)

SR-IM-IS

14

44

9

45

0.075

Rpn6

SR-CR-IS

0

6

1

15

–0.063

CG30053

SR-CR-IS

3

10

12

8

–0.369

nejire

GR-IS-TE

16

79

9

80

0.067

Tak1

GR-IM-IS

6

13

3

9

0.066

eIF-4a

GR-IM-IS

14

44

9

45

0.273

Rpt3

GR-CR-IS

2

7

0

16

0.222

Jra

GR-CR-IS

6

6

0

4

0.500

CG12054

GR-SR-IS

0

10

4

12

–0.250

RpL22

GR-SR-IS

1

6

0

3

0.143

RpL7

GR-SR-IS

3

6

0

8

0.333

RpS13

GR-SR-IS

2

3

0

1

0.400

Sos

GR-SR-IS

1

31

2

49

–0.008

zeste

GR-SR-IS

3

22

0

14

0.120

CG2807

GR-SR-IS

1

27

0

60

0.036

CycT

GR-SR-IS

5

29

5

15

–0.103

Rpn12

GR-SR-CR

1

9

0

1

0.100

  1. aThe two letter abbreviation codes for the phenotypic categories are: CR: Regulation of circadian rhythm, SR: Cell surface receptor signaling pathway, IS: Regulation of intracellular signal transduction, GR: Regulation of extent of cell growth, TE: Regulation of transposon integration, IM: Innate immune response