Genomic analysis of codon usage shows influence of mutation pressure, natural selection, and host features on Marburg virus evolution

Table 2 The synonymous codon usage patterns of MARV and its hosts

Codon (Amino acid)	RSCU			Codon (Amino acid)	RSCU
Codon (Amino acid)	MARV	H. sapiens	R. aegyptiacus	Codon (Amino acid)	MARV	H. sapiens	R. aegyptiacus
UUU (F)	1.23	0.92	0.68	UCU (S)	1.25	1.14	0.72
UUC (F)	0.77	1.08	1.32	UCC (S)	0.66	1.32	1.62
UUA (L)	1.72	0.48	0.18	UCA (S)	1.80	0.90	0.48
UUG (L)	1.24	0.78	0.78	UCG (S)	0.28	0.30	0.30
CUU (L)	1.08	0.78	0.72	AGU (S)	1.28	0.90	0.72
CUC (L)	0.64	1.20	1.50	AGC (S)	0.73	1.44	2.16
CUA (L)	0.80	0.42	0.30	AGA (R)	2.00	1.26	1.80
CUG (L)	0.53	2.40	2.52	CGU (R)	0.82	0.48	0.00
AUU (I)	1.35	1.08	0.78	CGC (R)	0.34	1.08	0.66
AUC (I)	0.73	1.41	1.86	CGA (R)	0.94	0.66	0.66
AUA (I)	0.92	0.51	0.36	CGG (R)	0.55	1.20	0.66
GUU (V)	1.38	0.72	0.36	AGG (R)	1.46	1.26	2.16
GUC (V)	0.96	0.96	0.92	UGU (C)	1.39	0.92	0.76
GUA (V)	0.80	0.48	0.28	UGC (C)	0.61	1.08	1.24
GUG (V)	0.86	1.84	2.44	CAU (H)	1.37	0.84	0.58
CCU (P)	1.51	1.16	1.56	CAC (H)	0.63	1.16	1.42
CCC (P)	0.77	1.28	1.16	CAA (Q)	1.35	0.54	0.58
CCA (P)	1.26	1.12	0.72	CAG (Q)	0.65	1.46	1.42
CCG (P)	0.46	0.44	0.56	AAU (N)	1.35	0.94	0.50
ACU (T)	1.21	1.00	1.04	AAC (N)	0.65	1.06	1.50
ACC (T)	0.62	1.44	1.72	AAA (K)	1.24	0.86	0.54
ACA (T)	1.85	1.12	1.12	AAG (K)	0.76	1.14	1.46
ACG (T)	0.33	0.44	0.08	GAU (D)	1.25	0.92	0.56
GCU (A)	1.37	1.08	1.04	GAC (D)	0.75	1.08	1.44
GCC (A)	0.90	1.60	1.48	GAA (E)	1.31	0.84	0.62
GCA (A)	1.47	0.92	0.84	GAG (E)	0.69	1.16	1.38
GCG (A)	0.27	0.44	0.64	GGU (G)	1.03	0.64	0.84
UAU (Y)	1.31	0.88	0.66	GGC (G)	0.52	1.36	0.84
UAC (Y)	0.69	1.12	1.34	GGA (G)	1.43	1.00	1.20
				GGG (G)	1.01	1.00	1.12

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