Fig. 2

Similarity among expression changes in the tolerant strains. a Changes in PCA scores during adaptive evolution. Starting from the parent strain, changes in the expression profiles during adaptive evolution are plotted as orbits in the two-dimensional PCA plane. b An example of the correlation between expression changes that occurred in two tolerant strains. The expression changes in strain E and F were plotted. Horizontal and vertical axes are log-transformed expression ratios with the parent strain, and each dot represents the expression change of the gene. All possible combinations are shown in Additional file 3: Figure S2