Fig. 5

Structure of mitochondrial DNA encoded MT-CO1 (red) (also see in 5b), MT-CO2 (yellow) (also see in 5c), and MT-CO3 (green) subunits from bovine heart cytochrome c oxidase at 2.8 Å (PDB: 1OCC) (5a). Amino acid sites in cyan are positively selected sites detected in this study (5a). White indicates key residues in proton translocation pathways: D-pathway and K-pathway in subunit I. Magenta indicates key residue for electron to enter and CuA liganded residues in subunit II