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Table 2 Location of putative alternative polyadenylation signals (PS) in the 3' UTR of AMBN cDNA sequences

From: Evolutionary analysis of selective constraints identifies ameloblastin (AMBN) as a potential candidate for amelogenesis imperfecta

Species

Length

PS1

PS2

PS3

PS4

PS5

3'UTR

ATTAAA

AATAAA

AATAAA

ATTAAA

AATAAA

Human

553

106-111

129-134

189-194

415-420

536-541

Bushbaby

483

77-83

100-105

157-162

344-349

466-471

Tree shrew

553

106-111

129-134

189-194

412-417

536-541

Mouse

543

-

127-132

184-189

403-408

526-531

Squirrel

539

105-110

128-133

188-193

406-411

521-526

Rabbit

549

106-111

129-134

189-194

410-415

532-537

Cow

555

106-111

129-134

189-194

419-424

538-543

Horse

556

106-111

129-134

189-194

-

539-544

Dog

557

107-112

130-135

190-195

-

540-545

Microbat

513

-

109-114

169-174

377-382

497-502

Elephant

556

-

126-131

186-191

-

537-542

Opossum

540

121-126

-

209-214

495-500

520-525

Platypus

441

116-121

-

-

-

426-431

Caiman

493

-

95-100

298-303

-

475-480

  1. TGA-------------PS1---PS2--------PS3-----------------------PS4--------------PS5--AAAAAAA
  2. The PS are given for 13 representative species of the main mammalian lineages and the crocodile. Bottom: schematical representation of PS locations on the human AMBN sequence from the stop codon (TGA) to the poly(A); an hyphen represents 10 nucleotides