Fig. 2

A summary of NarJ subfamily member operon associations and genetic arrangements. A diagrammatic summary of genes frequently co-occurring within a 10 ORF radius of NarJ subfamily member (narJ, dmsD, ycdY and torD) loci and operons are shown as labelled arrows. All identified ORFs/genes (labelled according to three letter gene abbreviations) are provided in their order of occurrence from each indicated locus (left-hand side). Solid lined unfilled arrows indicate ORF present at ≥80 % co-frequency occurrence and dashed lined unfilled arrows indicate ORF at ≤ 60 % co-frequency of occurrence to NarJ subfamily member loci (black filled arrows). ORF abbreviations listed in each arrow are as follows: biotin sulfoxide reductase molybdoenzyme family (bisC), DMSO reductase alpha molybdoenzyme containing subunit (dmsA/ dmsA1), DMSO reductase beta iron-sulfur subunit (dmsB), DMSO reductase membrane anchor subunit (dmsC), 200 amino acid protein of unknown function (DUF3306), 170–190 amino acid protein of unknown function (DUF3305), TAT pathway signal sequence domain-containing protein (fdh _tat), Fdh-N alpha molybdoenzyme subunit G (fdhG), fdh-N beta iron-sulfur subunits H1/H2 (fdhH1/fdhH2), Fdh-N gamma membrane anchor subunit I (fdhI), 4Fe-4S binding domain containing protein (fer4), FtsH protease membrane subunit (hflC), 4Fe-4S-cluster-containing hydrogenase component/ 4Fe-4S ferredoxin (hybA), NADPH-quinone reductase/ dehydrogenase (mdaB), nitrate reductase alpha molybdoenzyme subunit (narG), nitrate reductase beta iron-sulfur subunit (narH), nitrate reductase gamma membrane anchor subunit (narI), nitrate/ nitrite major facilitator transporter (narK), nitrate/ nitrite major facilliator transporter (narU), polysulfide reductase/ formate-dependent nitrite reductase membrane component (nrfD), major facilitator multidrug resistance transporter (mdtH), parvulin-like peptidyl-prolyl isomerase (ppiC), TMAO reductase I catalytic subunit (torA), TMAO reductase c-type cytochrome (torC), two-component regulatory system sensory histidine kinase (narX), response regulator of two-component regulatory system (narL), membrane-anchored diguanylate cyclase (ycdT), Zinc- binding alkaline phosphatase/ hydrolase (ycdX), 5 transmembrane inner membrane protein of unknown function DUF1097 (ycdZ), unknown lipoprotein DUF1439/ PRK10598 (yceB)