A refined model of the genomic basis for phenotypic variation in vertebrate hemostasis

Table 1 Mantel and partial Mantel’s tests of physiological genetics (MA) and phylogenetic distance matrices

	Functional component	Variable	R	p
Physiological genetic model	Endothelium	LRP8	0.589	0.021
	Platelets/Thrombocytes	GPIX	0.067	0.354
	Plasma Proteins	ApoH	0.689	0.017
		CC1Q	0.589	0.014
		FII	0.727	0.009
		PRCP	0.707	0.007
Physiological genetic model with phylogeny	Endothelium	LRP8	0.282	0.136
	Platelets/Thrombocytes	GPIX	−0.017	0.464
	Plasma Proteins	ApoH	0.489	0.027
		CC1Q	0.355	0.073
		FII	0.569	0.008
		PRCP	0.530	0.011

The regression coefficient (R) and associated p-values (p) are shown for i) the physiological genetic model, showing the results from Mantel tests for each variable, and ii) the physiological genetic model with phylogeny shows the results from partial Mantel tests controlling for phylogenetic distances (significant variables after correcting for FDR are highlighted in bold)

ISSN: 2730-7182