Fig. 4
From: Estrogen regulation of microcephaly genes and evolution of brain sexual dimorphism in primates
E2 suppresses the promoter activities of MCPH genes in SK-N-SH cells. a-d Quantification of promoter activity of ASPM, CDK5RAP2, MCPH1 and WDR62 using luciferase reporter gene assay. The SK-N-SH cells (derived from human neuroblastoma) were transiently transfected with vector containing human ERα