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Figure 1 | BMC Evolutionary Biology

Figure 1

From: Comparative functional pan-genome analyses to build connections between genomic dynamics and phenotypic evolution in polycyclic aromatic hydrocarbon metabolism in the genus Mycobacterium

Figure 1

Metabolic ambiguity of PAHs as nutrient or toxicant. The ring-cleavage process (RCP)—mono- or dioxygenation by ring-hydroxylating oxygenases (RHOs) or cytochrome P450 monooxygenases (CYPs), dehydrogenation by dihydrodiol dehydrogenase, and ring-cleavage by ring-cleavage dioxygenase—in mycobacterial PAH metabolism responsible for metabolic benefits is in the green colored area, while production of toxic PAH metabolites/byproducts and reactive oxygen species (ROS), which have the potential to cause PAH-adducts and oxidative DNA damage, is in the red colored area.

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BMC Ecology and Evolution

ISSN: 2730-7182

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