Skip to main content

Table 3 Inferred recombinant genotypes from analysis of the phased MH class IIα/IIβ PBR dataset

From: High intralocus variability and interlocus recombination promote immunological diversity in a minimal major histocompatibility system

Genotype Recombination breakpoint Mutation savings p-val
DAA-E2*9/DAB-E2*4 198-4896 9 0.0001
DAA-E2*3/DAB-E2*13 180-4896 9 0.0002
DAA-E2*12/DAB-E2*14 188-4890 7 0.0002
DAA-E2*13/DAB-E2*13 198-4890 6 0.0001
DAA-E2*7/DAB-E2*2 210-5007 6 0.0016
DAA-E2*2/DAB-E2*6 5058-5079 6 0.0004
DAA-E2*9/DAB-E2*2 198-4896 6 0.0001
DAA-E2*2/DAB-E2*9 193-5007 5 0.0021
DAA-E2*2/DAB-E2*10 4930-5007 5 0.0001
DAA-E2*14/DAB-E2*2 180-4896 5 0.0053
  1. Note: Recombination breakpoints for interlocus recombinants include 4630 bp separating the sequenced peptide binding regions of MHIIα and IIβ (see Figure 1).