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Figure 6 | BMC Evolutionary Biology

Figure 6

From: High intralocus variability and interlocus recombination promote immunological diversity in a minimal major histocompatibility system

Figure 6

Positively selected sites of the seahorse MH class II are concentrated in the inferred peptide binding groove of the mature protein. Quaternary structure models of the major histocompatibility class II molecule for (a) Mus musculus and (b) Hippocampus abdominalis, based on crystallographic reconstructions for Mus (pdb1es0). Surface structures of extracellular components of MH IIα (red) and MH IIβ (blue) are shown, as are (a) peptide-binding sites, and (b) sites inferred to be under positive selection in the seahorse (yellow and green for MH IIα and IIβ respectively).

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