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Figure 4 | BMC Evolutionary Biology

Figure 4

From: High intralocus variability and interlocus recombination promote immunological diversity in a minimal major histocompatibility system

Figure 4

Amino acid alignment of MH class IIα alleles. Alignment contains all seahorse alleles (Hiab) along with a selection of teleost fish sequences (Dicentrarchus labrax (Dila); Danio rerio (Dare); Gasterosteus aculateus (Gaac); Oryzias latipes (Orla); Takifugu rubripes (Taru); Tetraodon nigroviridis (Teni)) and human (Hosa). Sites identified as being under positive selection in the seahorse, are indicated, as well as those identified as peptide-binding sites in previous crystallographic analyses of human MHC II [2],[3]. Genbank/Ensembl identification codes indicated for publically available sequences. Corresponding nucleotide sequences for all seahorse MH class IIα alleles have been deposited in GenBank (KP259890-KP259907).

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BMC Ecology and Evolution

ISSN: 2730-7182

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