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Figure 1 | BMC Evolutionary Biology

Figure 1

From: Horizontal Gene Transfers in prokaryotes show differential preferences for metabolic and translational genes

Figure 1

Schematic diagram of changes in protein distances with HGT. (A) In a protein family where no horizontal transfer of gene has occurred, the protein tree will exactly follow species tree. In such a case, plotting genomic distances vs. protein distances will show a perfect correlation. (B) On the other hand, if a gene is horizontally transferred, e.g., from species SA to species SB, the protein tree will not resemble the species tree. In this case, some protein distances (like BC) will appear to be greater and some other protein distances (like AB) will appear to be smaller than the corresponding genomic distances. These outlying points (BC, AB) will result in disturbance in correlation and can be detected with Cook's distance.

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