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Table 1 KH tests verify the significance of breakpoints estimated by GARD analysis

From: Differential stepwise evolution of SARS coronavirus functional proteins in different host species

    

p-value

Dataset

Number of breakpoints

AICc improvement

Breakpoint location

LHS

RHS

Spike

9

588.485

776

1.000

0.220

   

933

0.059

0.427

   

1257

1.000

0.464

   

1485

1.000

1.000

   

2067

1.000

0.670

   

2301

0.002

0.002

   

2592

0.893

0.061

   

2916

0.085

0.988

   

3501

1.000

0.659

Replicase

2

30.414

1230

1.000

0.507

   

4398

1.000

0.040

3'-end ORFs

5

254.203

454

0.363

0.306

   

729

0.210

0.001

   

1091

0.010

0.078

   

1927

0.254

0.005

   

3321

1.000

0.353

  1. KH test was used in both directions to compare phylogenies constructed from the alignment segment to the left hand side (LHS) and right hand side (RHS) of each estimated breakpoint. All p-values have been adjusted by Bonferroni correction.
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BMC Ecology and Evolution

ISSN: 2730-7182

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