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Table 4 FMutSel LRT and parameter estimates with the M0 model

From: Molecular evolution of UCP1 and the evolutionary history of mammalian non-shivering thermogenesis

Locus

FMutSel â„“

FMutSel0 â„“

2Δℓ

p-value

ω

P+

S+

S-

UCP1

-10029.62

-10118.34

177.44

<0.001

0.129

0.40

1.42

-1.58

UCP2

-8657.37

-8777.49

240.24

<0.001

0.074

0.31

1.90

-2.44

UCP3

-8857.95

-9004.26

292.62

<0.001

0.099

0.41

1.57

-1.93

  1. FMutSelℓ is the log likelihood of the FMutSel substitution model; FMutSel0ℓ is the log likelihood of the FMutSel0 substitution model; 2Δℓ is the LR test statistic for comparing these two models; p is the p-value of the LR test; ω is the estimated ω value for the designated gene phylogeny using the global M0 model; P+ is the proportion of advantageous mutations that could occur across the gene; S+ is the selection coefficient for advantageous mutations; S- is the selection coefficient for disadvantageous mutations.