Relaxin gene family in teleosts: phylogeny, syntenic mapping, selective constraint, andexpression analysis

Table 2 Proposed nomenclature for relaxin family loci (RFL) in teleosts.

Teleost gene name	Human	Park et al.	Wilkinson et al.
			T. rubripes	D. rerio
insl5a	INSL5	RFLA1	TrRLX3d	DrRLX3b
insl5b	--	RFLA2	TrRLX3e	DrRLX3d
rln	RLN	RFLB1	TrRLX3c	--
rln3a	RLN3	RFLC2	TrRLX3a	DrRLX3a
rln3b	--	RFLC1	TrRLX3b	--
insl3	INSL3	RFLCII*	TrRLX3f	DrRLX3c

The proposed names for the six teleost RFL are given along with the nomenclature used for the orthologous genes in humans, and the nomenclature proposed by Park et al. (2008) and Wilkinson et al. (2005) in Takifugu rubripes and Danio rerio for teleost relaxin family genes. Park et al. (2008) propose that teleosts do not have an insl3 orthologue. They suggest that insl3 adopted its role in mammals after the divergence of Amphibia, and refer to the ancestral insl3 locus in amphibians as RFLCII.

ISSN: 2730-7182