Figure 5

The presence of mitochondrial N-terminal targeting signals (A) and mitochondrial Pfam domains (B) for human mitochondrial (mt) and non-mitochondrial (nonmt) proteins. N-terminal mitochondrial targeting signals were inferred for proteins in mt-cy families based on targetP predictions [38]. Mitochondrial Pfam domains refer to those domains that were found only in eukaryotic (excluding human) mitochondrial proteins [40].