Figure 1
From: Phylogenomic analysis of the cystatin superfamily in eukaryotes and prokaryotes
Vertebrate multidomain representatives of the cystatin superfamily: kininogens, fetuins A and B and HRGs. The rooted neighbor-joining tree shows the evolutionary relationships between the vertebrate-specific kininogen, fetuin and HRG orthologous families. NJ tree represents the bootstrap consensus following 1000 replicates, nodes with confidence values greater than 50% are indicated. Sequences were obtained from the GenBank, genus names and accession numbers are included.