Figure 2

WebLogo based on an alignment of type 1 and type 2 vertebrate ORs and B. floridae ORs. This WebLogo was created using an alignment of 64 vertebrate ORs (chicken, human, mouse, lamprey, amphibian and fish), 50 full-length B. floridae ORs and 11 partial B. floridae ORs. Approximately 200 positions were included in the alignment. The arrows indicate positions where blocks of sequence have been removed because they could not be aligned. For this reason, extracellular loop 2 (EL2) and transmembrane domain 5 (TM5) are missing from the WebLogo image. Transmembrane domains are represented by green bars and the boundaries were defined according to [45]. The intracellular and extracellular loops are labelled 'IL' and 'EL' respectively. The four conserved regions shaded in pink (labelled A-D) were used to generate a list of OR motifs (see Table 1).