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Figure 3 | BMC Evolutionary Biology

Figure 3

From: Evidence for a rapid rate of molecular evolution at the hypervariable and immunogenic Mycobacterium tuberculosis PPE38 gene region

Figure 3

RD5 and RD5-like deletions seen in MTBC isolates. This region is susceptible to frequent large deletions. Here we show the genes surrounding PPE38 along with the deleted regions characterised in 5 non-M. tuberculosis MTBC members [2225, 32], along with the deletions detected in the M. tuberculosis whole genome sequences T92 and 94_M4241A. A red arrow indicates the presence and direction of IS6110 at a deletion point. Deletions caused by homologous recombination between PPE39 and PPE40 in M. bovis BCG and 94_M4241A are also shown. Numbering refers to gene nucleotide positions.

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