Figure 1

Phylogenetic reconstruction of the evolutionary relationships between members of the H37Rv M. tuberculosis PPE protein family members. The phylogenetic tree was constructed from a phylogenetic analysis done on the 180 aa N-terminal domains of the PPE proteins. Results show the division of PPE proteins into 5 sublineages with PPE38 (Rv2352c, highlighted in green) located at the border of sublineages IV (SVP subfamily) and V (MPTR subfamily). Reproduced from ref [2] with permission from the authors.