Figure 1
From: Evolutionary history of selenocysteine incorporation from the perspective of SECIS binding proteins
SECIS binding protein topology. Alignment of SBP2 and SBP2L across the species indicated generated with the MUSCLE module in Geneious (Biomatters Ltd). The N and C-terminal portions of SBP2 and SBP2L were independently aligned. Residues were colored using JalView based on BLOSUM62 score [[37]; darker colors indicate higher similarity]. The SBP2L N-terminal sequence is red to denote that it is a separate alignment from that for SBP2. Globally conserved motifs motifs include the Sec incorporation domain (SID), the RNA binding domain (RBD), LSAD15-26 and PFVQ44-56. Shading of species names is used for the identification of SBP2 classes as described in the text.