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Figure 5 | BMC Evolutionary Biology

Figure 5

From: FGFRL1 is a neglected putative actor of the FGF signalling pathway present in all major metazoan phyla

Figure 5

Embryonic expression of amphioxus FGFRL1. Anterior is towards the left, and dorsal is up in the side views. Scale bars = 50 μm. (A) Side view of a gastrula stage embryo showing high expression of FGFRL1 in the anterior dorsal region. (B) Side view of an early neurula stage embryo. (C) Dorsal view of the embryo shown in (B). (D) Side view of a mid-neurula stage embryo with expression in the anterior region of the mesendoderm and neuroectdoderm as well as in the most anterior epidermis. (E) and (D) Dorsal views of the embryo shown in (D). (G) Side view of a late neurula stage embryo with labelling in the notochord, mainly in its most anterior part (white arrowhead), in the cerebral vesicle (black arrowhead) as well as in the anterior-most epidermis and in the pharyngeal endoderm. (H) Side view of a late neurula stage embryo showing expression in the cerebral vesicle (black arrowhead), in the notochord, mainly in its most anterior region (black arrow), and in the endoderm, with a high level in the region of the club-shaped gland anlagen (double black arrowhead). (I) Side view of the head of a larva. FGFRL1 is expressed in the cerebral vesicle around the frontal eye (black arrowhead), in the notochord with a high level in the most rostral region (black arrow), in the pre-oral pit (double black arrowhead), in the anterior region of the pharyngeal cavity (white arrow) and in the club-shaped gland (white arrowhead). (J) Side view of the tail of the specimen shown in (I) with labelling in the tailbud (black arrow) and in the anus (black arrowhead).

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