Figure 2

A phylogenetic tree of the bacterial EF-Tu and eukaryotic EF-1α inferred with PROCOV under WAG + the general covarion model. Brackets refer to the amino acids of the two groups at position 256, a site illustrating a non-typical covarion pattern where both eukaryotic (EF-1α) and bacterial (EF-Tu) sequences are very variable. Changes in EF-1α are more radical (i.e. substitutions between amino acid with different physicochemical properties) whereas those in EF-Tu are structurally more conserved changes.