Figure 2
From: SNP@Evolution: a hierarchical database of positive selection on the human genome
Using EDAR to demonstrate the output of a data query. After submitting EDAR as the search term, all hit data are provided in three tables. The regional statistics indicate whether the query is localized in a low HET region in a certain population or in a highly differentiated region among populations. The gene table with the sequence accession ID, gene symbol, and OMIM ID provides ES values of HET and P-value of iHS of each HapMap geographical group, as well as the ES value of F ST to show population differentiation. Finally, in addition to the rs# and its locations at both the chromosome and gene, SNPs of EDAR are displayed with individual HET and iHS of each population followed with F ST . The number above the third table indicates the total number of the SNPs identified in the query (only the first 7 were shown in the figure in this example). To illustrate selection related signals, the SNP outliers of iHS and F ST , as well as the extra ES values (>0.95) of HET and F ST , are highlighted in the tables.