Figure 4

Two independent BigFoot runs on the α MRE enhancer in 12 vertebrate species. Despite having very different starting points, the two runs give essentially identical results, indicating convergence of the sampling distribution. The locations of seven previously identified binding sites are displayed above the posterior probabilities. The only binding site not detected with greater than 95% probability, bs2, is directly adjacent to a weakly conserved region (bsAlt) that is undetected by other methods due to alignment errors.