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Figure 1 | BMC Evolutionary Biology

Figure 1

From: Does negative auto-regulation increase gene duplicability?

Figure 1

Known correlates of duplicability have no confounding effect. E. coli transcription factors under negative, positive or no auto-regulation are compared with regard to (A) protein length, (B) the number of different protein domains, (C) the number of genes present in the operon which they form part of, and (D) the proportion of under-wrapped residues, all of which are known correlates of duplicability. There are no significant differences between negative auto-regulators and transcription factors without auto-regulation. The only significant difference between regulatory types is an enrichment of positive auto-regulators in polycistronic (operon size >1) transcripts (P = 0.0002). See Table 1 and main text for sample sizes. AR: auto-regulation.

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