Conservation of the glucan phosphatase laforin is linked to rates of molecular evolution and the glucan metabolism of the organism

Table 1 Molecular evolution and conservation of lafoin.

Organism	laforin gene	moleuclar evolution	reference
Branchiostoma	present	slow	42
Ciona intestinalis	absent	accelerated	42, 44, 48
Caenorhabditis elegans	absent	accelerated	44, 46, 48
Drosophila	absent	accelerated	40, 43, 44, 46, 48
Echinoderms	absent	accelerated	40
Hydra	absent	accelerated	43, 44
Monosiga brevicollis	absent	accelerated	43, 44
Nematostella/Cnidaria	present	slow	42, 43, 44, 46, 47
sponge	absent	accelerated	43, 44
vertebrates	present	slow	40, 42, 43, 44, 46, 47, 48
yeasts	absent	accelerated	44

Rates of molecular evolution are defined in these studies as either substitutions per amino acid and/or position and phase of introns

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