Modular organization of the central domain of epiplasmins. A-Alignment of the seven repeated motifs in central domains of P. tetraurelia and T. thermophila epiplasmins. Two paralogs in P. tetraurelia and one T. thermophila protein share the first half of the epiplasmin central domain. B-HCA representation of these motifs is used to consider the position of conserved amino acids in relation with the hydrophobic clusters. This shows a spatial proximity between conserved proline and tyrosine (as mentioned in the discussion).