Comparative analysis of P. tetraurelia and T. thermophila epiplasmins using DNA sequence alignment. Five groups (1 to 5) were distinguished, based on node strength. According to hydrophobic cluster analysis, groups 1, 3 and 5 regroup 30 symmetric epiplasmins, group 2 represents 11 asymmetric epiplasmins, and group 4, 10 atypical epiplasmins. Results of large scale synteny analysis are reported as a red strand over the tree topology. Nodes corresponding to the 'ancient' and the 'old' WGD are circled in red and blue, respectively. EST numbers are compiled for each sub-group.