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Table 2 Candidate transcripts upregulated in hybrids compared to X. laevis.

From: Gene expression analysis of the ovary of hybrid females of Xenopus laevis and X. muelleri

ProbeID

GenBankID

Target Gene

GeneSymbol

Description/Molecular Function

Mean Laevis

SD Laevis

Mean Hybrid

SD Hybrid

L-H

adj.P.Val

Xl.4605.1.A1_at

BG552470

EST

MGC83384

 

3.41

0.39

7.63

0.44

-4.22

0.0041

Xl.19075.1.A1_at

BI675584

EST

 

Weakly similar to HES2 (Hairy and enhancer of split 2) (H. sapiens)

5.53

1.29

9.67

0.27

-4.14

0.0205

Xl.24502.1.S1_at

BJ098608

EST

 

Weakly similar to forkhead box P2; (H. sapiens)

4.56

0.70

8.65

0.00

-4.09

0.0060

Xl.23573.1.S1_at

BC041496.1

thymine-DNA glycosylase

TDG

Hydrolase activity, acting on glycosyl bonds

5.55

1.16

9.22

0.15

-3.67

0.0210

Xl.16239.1.A1_at

BJ039322

EST

  

5.39

1.36

8.66

0.46

-3.27

0.0405

Xl.8630.1.S1_s_at

BC045272.1

MGC53990

MGC53990

Similar to serum-inducible kinase; protein serine/threonine kinase act.

4.74

0.36

8.01

0.75

-3.26

0.0062

Xl.21956.1.S1_at

BC042271.1

MGC53461

MGC53461

 

8.39

0.22

11.57

0.00

-3.18

0.0041

Xl.24699.1.S1_at

CB984321

EST

MGC79012

Highly similar to alpha cardiac actin (H. sapiens)

3.65

0.36

6.51

1.79

-2.85

0.0327

Xl.10600.1.S1_at

BE491023

EST

  

4.88

0.94

7.68

0.25

-2.80

0.0256

Xl.11324.1.A1_at

BG552091

EST

  

3.44

0.46

6.23

0.11

-2.79

0.0064

Xl.13010.1.A1_at

BJ099673

EST

  

5.43

0.46

8.22

1.89

-2.79

0.0417

Xl.14915.1.A1_at

BM180884

EST

  

5.11

0.30

7.72

0.35

-2.61

0.0057

Xl.13666.1.A1_x_at

BJ091634

EST

  

7.61

0.80

10.17

0.37

-2.57

0.0230

Xl.24516.1.S1_at

CB560511

EST

LOC495356

Weakly similar to Apolipoprotein E precursor (H. sapiens); lipid binding

6.41

0.60

8.93

1.00

-2.52

0.0244

Xl.13831.3.S1_at

BJ075928

EST

  

5.64

0.45

8.05

0.17

-2.41

0.0094

Xl.24058.1.S1_at

BI940804

EST

MGC82121

Highly similar to histone H2A.FZ variant, isoform 1(H. sapiens)

6.99

0.28

9.40

0.09

-2.41

0.0057

Xl.16509.1.A1_at

BJ084267

EST

  

4.04

0.35

6.44

1.00

-2.40

0.0185

Xl.433.2.S1_at

BC044959.1

neurotrophin receptor B

trkb-b

Protein amino acid phosphorylation

3.68

0.40

6.01

0.00

-2.33

0.0076

Xl.19610.1.A1_at

BJ084191

EST

 

Similar to Angiopoietin-1 receptor precursor (mTIE2)

4.48

0.05

6.81

0.36

-2.33

0.0043

Xl.75.1.S1_at

D78003.1

c4

c4

Endopeptidase inhibitor activity i fourth component of complement

4.09

0.47

6.41

0.00

-2.32

0.0101

Xl.882.1.S1_at

U07179.1

Ldehydrogenase A

ldha

Oxidoreductase activity

5.29

0.94

7.60

0.06

-2.31

0.0387

Xl.17327.1.A1_at

BI448285

EST

MGC68503

 

4.77

0.49

7.07

0.19

-2.29

0.0117

Xl.747.1.S1_at

AF170341.1

galectin-1

MGC64502

Sugar binding

5.51

0.21

7.80

0.55

-2.29

0.0075

Xl.545.1.S1_at

AF170344.1

metastasis associated 1

mta2

Transcription factor activity, regulation of transcription

7.85

0.51

10.14

0.13

-2.29

0.0124

Xl.23647.1.S1_at

BC047974.1

cell death 2

pdcd2

Apoptosis

4.11

0.36

6.34

0.40

-2.23

0.0096

Xl.19047.1.A1_at

BI478140

Coatomerprotein

copa

ER to Golgi vesicle-mediated transport i

8.05

0.35

10.28

0.01

-2.23

0.0071

Xl.9113.1.A1_at

BG346438

chimerin

chn1

Signal transduction

6.10

0.76

8.32

0.12

-2.22

0.0276

Xl.16847.1.A1_at

BJ052360

EST

  

4.22

0.74

6.44

0.36

-2.22

0.0279

Xl.13666.1.A1_at

BJ091634

EST

  

6.81

0.77

8.97

0.54

-2.16

0.0350

Xl.721.1.S1_at

L09728.1

transcription factor DLL4

Dlx2

Regulation of transcription, DNA-dependent

7.89

0.58

10.04

0.35

-2.15

0.0199

  1. Top 30 candidate transcripts upregulated in hybrids and differentially expressed between females of X. laevis and hybrids. Expression values are in log2 scale; SD = standard deviation of expression values. P values are adjusted according to FDR moderated t-tests.