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Table 2 Inferred amino acid replacements in COX2p and COX4p that occur in proximity to positively selected sites in COX5Ap among anthropoid primate stem lineages.

From: Molecular evolution of the cytochrome c oxidase subunit 5 A gene in primates

COX5Ap

COX2p

COX4p

Residue

Lineage

Residue

Lineage

Residue

Lineage

5 (H to Q)

Ape stem

52 (H to N)

Catarrhine* stem

  

(H to S)

New World monkey stem

54 (S to N)

Catarrhine stem

  
  

55 (T to I)

Catarrhine stem

  
  

56 (M to T)

Catarrhine stem

  
  

56 (T to S)

Large-bodied ape stem

  
  

57 (D to N)

New World monkey stem

  

38 (G to T)

Anthropoid stem

52 (H to N)

Catarrhine stem

  
  

54 (S to N)

Catarrhine stem

  
  

55 (T to I)

Catarrhine stem

22 (Y to H)

Ape stem

  

56 (M to T)

Catarrhine stem

  
  

56 (T to S)

Large-bodied ape stem

  

41 (L to M)

Ape stem

52 (H to N)

Catarrhine stem

  
  

54 (S to N)

Catarrhine stem

  

64 (A to T)

Anthropoid stem

  

63 (Q to K)

Catarrhine stem

70 (V to A)

Anthropoid stem

  

22 (Y to H)

Ape stem

  1. Interaction is taken as a distance < 10 Ã… between residues.
  2. *Catarrhines include Old World monkeys and apes, including humans