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Table 3 Functional divergence estimated in 53 vertebrate bestrophin paralogues

From: Molecular evolution and functional divergence of the bestrophin protein family

Comparison θa SEb(θ) LRTc (θ) Pd Probability cutoffe
Best1 vs Best2 0.097 0.076 1.640 0.024541 -
Best1 vs Best3 0.142 0.043 10.762 0.000488 -
Best1 vs Best4 0.217 0.039 30.099 8.88557e-8 0.70
Best2 vs Best3 0.380 0.073 27.152 6.32074e-9 0.80
Best2 vs Best4 0.320 0.075 18.120 9.855e-10 0.64
Best3 vs Best4 0.260 0.059 19.338 9.477e-10 0.70
  1. a θ is the coefficient of functional divergence.
  2. b SE, standard error.
  3. c LRT (θ) is a likelihood ratio test.
  4. d significance level (Pc) calculated by the method of Fisher's transformation and corrected by Bonferroni.
  5. e Probability cut-off is the minimal posterior probaility for amino acids causing functional divergence.