Figure 3

Many N-terminal effector domains of the predicted zebrafish NLR-C molecules are recognized as pyrin/PAAD-DAPIN domains based on the HMM logo. Some examples are shown, with conserved amino acids [A]. Other N-terminal sequences were observed for NLR-C molecules, which were confirmed in the EST databases at TIGR [B]. TC326097 encodes a pyrin domain, whereas TC353741 and TC343155 represent undefined N-terminal domains such as those denoted by 'X' in Figure 2.