Table 3 Deletion mutants of module variants exhibit differential growth patterns when cultured on various carbon sources.
From: Complex fate of paralogs
Module variant paralogs | Deletion phenotype |
|---|---|
COX5A/COX5B | COX5A knockout: reduced fitness when no glucose |
KIP1/CIN8 | CIN8 knockout: unrestricted growth only on glycine |
BUL2/BUL1 | BUL1 knockout: reduced fitness on ethanol |
DID4/VPS24 | DID4 knockout: severely reduced growth on lactate |
NOT5/NOT3 | NOT3 knockout: severely impaired growth on glycine NOT5 knockout: growth severely impaired in all conditions tested |
REG2/REG1 | REG1 knockout: limited growth on glucose |