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Table 1 Paralogs in complexes.

From: Complex fate of paralogs

 

Intra-complex

Bi-complex

Overhangs

 

# proteins

observed/expected*

# proteins

observed/expected

# proteins

Paralogs

216

46 (P < 10-3)

62

0.3 (P < 10-3)

58

Comments

110 dosage increase

24 interacting homologs

54 module variants

Mostly old duplications,

5× less WGD paralogs (P < 4*10-4)

 
  1. We note a strong over-representation and a statistically significant, many-fold enrichment (intra-complex) or depletion (bi-complex) compared to a null model for paralog evolution.
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BMC Ecology and Evolution

ISSN: 2730-7182

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