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Figure 2 | BMC Evolutionary Biology

Figure 2

From: The evolution of TEP1, an exceptionally polymorphic immunity gene in Anopheles gambiae

Figure 2

Divergence between TEP1s and TEP1r alleles. The proportion of sites that differ between the TEP1s and TEP1r alleles are plotted against position for all silent sites, synonymous sites, and non-synonymous sites). Genomic sequence spanned by the macroglobulin domains 1–8 (MG), a linker (LNK), a β-sheet and the thioester-containing domain (TED) are marked below the x-axis. Also marked are exons (solid black bars) and a region of putative gene conversion from TEP6 (grey bar, see main text for details). For zero to 5 kbp, 14 TEP1s and 15 TEP1r haplotypes were used; for 5 kbp to end, 6 TEP1s and 5 TEP1r haplotypes were used. Moving windows were 100-site for silent and synonymous sites, 300-site for non-synonymous sites and gaps in K silent correspond to regions with large indels and/or no discernable alignment between TEP1s and TEP1r haplotypes.

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