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Table 1 List of sequences included in the phylogenetic analyses.

From: D- and L-lactate dehydrogenases during invertebrate evolution

L-LDH
EC 1.1.1.27
    
Assignment Organisms   Accession number Reference
LDH Aedes aegypti yellow fever mosquito [Swiss-Prot:Q16ND1] [43]
LDH-A Alligator mississippiensis American alligator [Swiss-Prot:Q9PW06] [13]
LDH-B Alligator mississippiensis American alligator [Swiss-Prot:Q9PW05] [13]
LDH Anopheles gambiae African malaria mosquito [Swiss-Prot:Q7Q981] [44]
LDH Arabidopsis thaliana mouse-ear cress [Swiss-Prot:O49191] Dolferus et al. 1998 unpublished
LDH Caenorhabditis briggsae nematode [Swiss-Prot:Q61ZF2] [45]
LDH Caenorhabditis elegans nematode [Swiss-Prot:Q27888] [46]
LDH Capitella capitata segmented worm gi 134102 unpublished
LDH Carcinus maenas green crab [Swiss-Prot:DY308423] [47]
LDH-B Chelodina siebenrocki turtle [Swiss-Prot:Q6S5M2] Ho and Li 2003 unpublished
LDH Ciona intestinalis tunicate gi 149293 unpublished
LDH-A Cyprinus carpio common carp [Swiss-Prot:Q9W7K5] Tsoi et al. 1998 unpublished
LDH Clonorchis sinensis flatworm gi 56131044 unpublished
LDH-A Danio rerio zebrafish [Swiss-Prot:Q9PVK5] Tsoi et al. 1998 unpublished
LDH-B Danio rerio zebrafish [Swiss-Prot:Q9PVK4] Tsoi et al. 1998 unpublished
LDH-A Daphnia pulex water flea gi 230172 unpublished
LDH-B Daphnia pulex water flea gi 61140 unpublished
LDH Drosophila melanogaster fruit fly [Swiss-Prot:Q95028] [48]
LDH Drosophila pseudoobscura fruit fly [Swiss-Prot:Q29FH9] [49]
LDH-A Fundulus heteroclitus killifish [Swiss-Prot:Q92055] [50]
LDH-B Fundulus heteroclitus killifish [Swiss-Prot:P20373] [9]
LDH-C Fundulus heteroclitus killifish [Swiss-Prot:Q06176] [51]
LDH-A Gallus gallus chicken [Swiss-Prot:P00340] [52]
LDH-B Gallus gallus chicken [Swiss-Prot:P00337] Tsoi et al. 1998 unpublished
LDH-A Helobdella robusta segmented worm gi 115469 unpublished
LDH-B Helobdella robusta segmented worm gi 156879 unpublished
LDH-C Helobdella robusta segmented worm gi 166102 unpublished
LDH-A Homo sapiens human [Swiss-Prot:P00338] [53]
LDH-B Homo sapiens human [Swiss-Prot:P07195] [54]
LDH-C Homo sapiens human [Swiss-Prot:P07864] [55]
LDH-A Hordeum vulgare barley [Swiss-Prot:P22988] [20]
LDH-B Hordeum vulgare barley [Swiss-Prot:P22989] [20]
LDH Litomosoides sigmodontis nematode [GenBank:DN558179] Gregory W. 1995 unpublished
LDH-A Monodelphis domestica gray short-tailed opossum [Swiss-Prot:Q9XT87] Tsoi et al. 1998 unpublished
LDH-B Monodelphis domestica gray short-tailed opossum [Swiss-Prot:Q9XT86] Tsoi et al. 1998 unpublished
LDH-A Mus musculus house mouse [Swiss-Prot:P06151] [56]
LDH-B Mus musculus house mouse [Swiss-Prot:P16125] [57]
LDH-C Mus musculus house mouse [Swiss-Prot:P00342] [58]
LDH Petrolisthes cinctipes flat porcelain crab [GenBank:FE768558FE768559] [35]
LDH Petromyzon marinus sea lamprey [Swiss-Prot:P33571] [10]
LDH-A Squalus acanthias spiny dogfish [Swiss-Prot:P00341] [59]
LDH-B Squalus acanthias spiny dogfish [Swiss-Prot:Q9YI05] [60]
LDH Strongylocentrotus purpuratus purple urchin [GenBank:XP_001196488] unpublished
LDH Styela plicata tunicate [Swiss-Prot:O44340] [7]
LDH Tribolium castaneum red flour beetle [GeneBank:XM_963110] unpublished
LDH-A Xenopus laevis African clawed frog [Swiss-Prot:P42120] [11]
LDH-B Xenopus laevis African clawed frog [Swiss-Prot:P42119] [11]
LDH-C Xenopus laevis African clawed frog [Swiss-Prot:P42121] [11]
LDH Zea mays maize [Swiss-Prot:P29038] [61]
D-LDH EC
1.1.2.4
    
  Arabidopsis thaliana mouse-ear cress [GeneBank:NM_120741] unpublished
  Bos taurus cattle [Swiss-Prot:Q148K4] Moore et al. 2006 unpublished
  Caenorhabditis elegans nematode [GeneBank:NP_001023872] unpublished
DLD1 Candida sphaerica yeast [Swiss-Prot:Q12627] [62]
  Canis familiaris dog [GeneBank:XP_852976] unpublished
  Ciona intestinalis tunicate gi: 289925 unpublished
  Capitella capitata segmented worm gi: 177524 unpublished
  Danio rerio zebrafish [GeneBank:NP_956157] [63]
  Daphnia pulex water flea gi: 302238 unpublished
  Lottia gigantea gastropod gi: 229861 unpublished
  Helobdella robusta segmented worm gi: 185793 unpublished
  Homo sapiens human [Swiss-Prot:Q86WU2] [5]
  Monodelphis domestica gray short-tailed opossum [GeneBank:XP_001375142] unpublished
  Mus musculus house mouse [Swiss-Prot:Q7TNG8] [5]
  Nematostella vectensis starlet sea anemone [GeneBank:XP_001626025] unpublished
  Pan troglodytes chimpanzee [GeneBank:XP_001139010] unpublished
  Rattus norvegicus Norway rat [Swiss-Prot:Q7TPJ4] Xu et al. 2003 unpublished
DLD1 Saccharomyces cerevisiae baker's yeast [Swiss-Prot:YDL174C] [64]
  Strongylocentrotus purpuratus purple urchin [GeneBank:XP_796456] unpublished
  Tetraodon nigroviridis Green puffer [Swiss-Prot:Q4T6R2] [65]
  Xenopus laevis African clawed frog [Swiss-Prot:A1L2R0] [66]