Hybridization of PKD1 probes on human and bonobo chromosomes. One- and two-colour FISH of human PKD1 BAC clone RP11-304L19 (BAC) and PKD1 cDNA clone (cDNA) to prometaphase chromosome 16 of human (HSA) (a-c) and to prometaphase chromosome 16 of the bonobo (PPA) (d-f). The colours of the inserted clone names correspond to those of the fluorescence signals (biotin-FITC: green; digoxigenin-TRITC: red; yellow: overlapping green and red signals) on the DAPI-counterstained plates. "qh" and "ph" mean long arm and short arm heterochromatin. Centromeres are marked by small bars.