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Figure 3 | BMC Evolutionary Biology

Figure 3

From: Ultraconserved coding regions outside the homeobox of mammalian Hox genes

Figure 3

Sliding window analysis of synonymous and nonsynonymous nucleotide substitutions between human and dog or human and mouse for the orthologous gene group 6. The window size is 120 nucleotides and moves every single codon. The X axis indicates the position of the last nucleotide of each sliding window comparison. The regions of homeobox motif and UCRs are highlighted in yellow and light blue, respectively. The synonymous and nonsynonymous substitutions are measured by the proportion of synonymous differences per synonymous site (pS), and the proportion of nonsynonymous differences per nonsynonymous site (pN), respectively. We used pS and pN here because these measures are model free and range from 0 to 1 (see Nei and Kumar 2000).

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