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Figure 9 | BMC Evolutionary Biology

Figure 9

From: Evolutionary history of the alpha2,8-sialyltransferase (ST8Sia) gene family: Tandem duplications in early deuterostomes explain most of the diversity found in the vertebrate ST8Sia genes

Figure 9

Schematic drawing of the evolution of the ST8Sia gene family. Model for the evolution of the ST8Sia genes based on evidence from protein sequence phylogeny, conserved synteny of genomic loci between species and paralogous relationships between the genomic regions of human ST8Sia. The diagram takes into account that the four ancestral groups of ST8Sia (four bottom coloured boxes) predate the WGD R1 and WGD R2, which occurred early in the vertebrate lineage. Dotted lines are intermediate steps. Open red circles are gene losses on the phylogenetic tree. Open boxes represent gene loss following block duplications. The broken lines correspond to the two main WGDs R1 and R2.

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