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Figure 1 | BMC Evolutionary Biology

Figure 1

From: Evolutionary history of the alpha2,8-sialyltransferase (ST8Sia) gene family: Tandem duplications in early deuterostomes explain most of the diversity found in the vertebrate ST8Sia genes

Figure 1

A. Multiple sequence alignments of the vertebrate and invertebrate ST8Sia reveal a new family motif named C-term. Black letters with a yellow background represent conserved positions at the 90% level for all the ST8Sia sequences whereas the orange background represents conserved positions at > 50%. B. Sequence logo of the ST8Sia family motifs. Relative positions in the ST8Sia sequences of the ST8Sia family-motif (a) described by Patel and Balaji [13] and the new C-term motif (b) found in all the ST8Sia sequences. In the logos, amino acids are colored according to their chemical properties: polar amino acids (G, C, S, T, Y) are green, basic (K, R, H) are blue, acidic (D, E) are red, hydrophobic (A, V, L, I, P, W, F, M) are black and neutral polar amino acids (N, Q) are pink. The overall height of the stack indicates the sequence conservation at a given position, while the height of symbols within the stack indicates the relative frequency of each amino at that position [69, 70].

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