Distribution of SET-domain genes in the three kingdoms. Saccharomycotina and Pezizomycotina fungi are shown as "Sac" and "Pez", respectively, among the fungal kingdom. Species or group-specific duplication events of SET-domain genes are illustrated by dashed arrows. SET5/6 related filamentous fungi are shown as "SET-fil". Arrows marked with * indicate that such relationship is not significant and inconclusive. SET-MYND and SUV3-9 are found in S. pombe as well as Pezizomycotina fungi, but missing from Saccharomycotina fungi. This is indicated by the arrows marked with "(-Sac)".