hsp70 genes in the human genome: Conservation and differentiation patterns predict a wide array of overlapping and specialized functions

Brocchieri, Luciano; Conway de Macario, Everly; Macario, Alberto JL

doi:10.1186/1471-2148-8-19

Table 6 Expression levels of hsp70 genes in various human tissues^a

From: hsp70 genes in the human genome: Conservation and differentiation patterns predict a wide array of overlapping and specialized functions

TISSUE/GENE	HSPA9B	HSPA5	HSPA1A	HSPA1B	HSPA1L	HSPA8	HSPA2	HSPA6	STCH	HSPA14	HSPA4	HSPA4L	HSPH1	HYOU1	HSPA12A	HSPA12B
Blood	336	172	546	72	0	2412	9	118	36	36	18	0	109	54	0	0
Bone	341	505	150	0	0	1326	0	41	54	54	164	13	123	109	0	13
Bone marrow	448	529	61	81	0	1691	40	20	40	40	61	0	142	448	0	0
Brain	364	99	805	235	3	3355	753	14	127	58	45	43	308	120	88	6
Connective	289	373	476	56	18	2943	37	18	84	37	74	0	93	130	37	9
Adipose	73	591	2885	591	73	1035	0	73	0	73	73	0	147	73	73	0
Ear	177	118	769	0	0	591	118	0	0	0	59	59	177	0	59	0
Liver	306	316	397	62	0	1198	4	0	23	28	52	19	47	306	0	0
Pancreas	150	388	480	155	0	818	4	18	27	36	82	4	77	128	9	0
Adrenal gland	538	348	1805	411	0	3959	63	95	95	31	158	0	190	221	95	0
Parathyroid	616	47	0	0	0	568	0	0	0	331	0	47	47	0	237	0
Thyroid	523	1571	776	271	0	1318	0	0	0	72	36	18	144	198	162	18
Pituitary gland	223	503	167	0	55	1734	55	55	0	55	167	55	559	55	223	0
Placenta	219	293	169	13	0	856	219	53	79	66	89	13	86	86	13	49
Eye	129	177	220	57	14	989	43	28	96	43	124	28	67	91	43	0
Embryonic	306	701	98	41	0	1304	15	0	67	77	171	5	124	213	5	0
Abdominal cav.	964	642	98	49	0	2743	0	0	24	24	247	24	98	123	0	0
Cervix	537	247	123	103	0	1177	20	0	103	82	123	20	82	103	0	20
Ovary	93	409	74	83	0	1581	9	18	46	37	102	0	37	130	55	18
Uterus	287	608	721	266	0	2334	125	8	79	41	133	16	95	125	20	8
Prostate	153	262	1410	237	6	1653	32	19	44	38	115	32	44	102	32	0
Testis	383	252	197	44	67	2222	411	3	140	73	118	220	389	130	31	9
Bladder	423	195	782	1108	0	1858	0	130	228	97	0	65	195	32	0	0
Kidney	349	130	931	214	9	4470	204	9	97	23	69	55	158	274	93	46
Tongue	590	132	1388	118	0	1905	162	14	29	103	236	29	280	44	14	0
Larynx	132	498	365	66	0	565	0	0	0	66	0	0	66	66	33	0
Pharynx	69	139	69	0	0	765	69	0	0	0	0	139	0	69	0	0
Salivary gl.	96	0	0	0	0	387	145	0	48	96	145	48	0	48	0	0
Heart	246	190	1692	347	11	2129	67	44	33	22	33	11	56	44	33	67
Lymph node	165	176	10	10	0	590	0	0	82	217	103	0	176	10	41	0
Lymph	334	44	0	0	0	1381	0	0	0	0	89	0	111	111	0	0
Tonsil	0	0	115	0	0	463	57	0	0	231	115	0	57	57	0	0
Spleen	302	113	7292	1416	0	5516	94	75	18	18	18	0	37	56	18	94
Thymus	279	39	1982	399	0	4444	13	172	53	53	39	13	172	0	0	13
Mammary gl.	524	647	647	104	5	2145	17	17	64	52	169	11	81	1119	46	0
Muscle	393	113	262	52	0	2963	26	8	26	34	87	52	139	157	43	0
Lung	247	213	1467	153	8	1166	17	76	48	25	102	22	125	201	14	17
Trachea	224	40	2595	797	0	3310	61	265	265	40	20	163	408	143	0	20
Skin	432	173	358	42	0	2861	179	26	21	47	226	0	131	158	21	5
Umbilical cord	148	148	0	0	0	1782	816	0	0	0	0	0	0	297	0	74
Vascular	411	176	1038	58	0	8247	19	0	117	0	0	19	176	842	39	0
Small intestine	357	447	3914	380	22	4853	357	0	67	22	134	0	134	201	0	0
Colon	251	374	320	103	0	2986	9	29	24	39	123	9	118	226	4	4
Stomach	126	466	641	145	0	1856	38	29	0	19	456	9	204	58	0	0
Esophagus	578	1261	2732	1839	0	1839	262	157	52	105	105	52	262	683	0	0
Nerve tissue	156	509	3725	470	0	1215	39	39	0	39	39	0	196	196	235	39

^aEach number represents the number of Gene ESTs times 10⁶ over total number of Tissue ESTs, as reported in the NCBI UniGene database (2/2007). Boldface highlights the maximum for each Gene (two very close maxima are highlighted for HSPA12A). Abbreviations: cav., cavity; gl., gland.

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